Welcome to the Probabilistic Methods for Estimation of Uncertain Systems (PROMETHEUS) Laboratory! The PROMETHEUS Lab conducts research to solve complex and challenging problems in estimation, with specific emphasis in space domain awareness and spacecraft navigation. We develop novel theoretical and computational methods that address problems in nonlinear, non-Gaussian uncertainty propagation; Bayesian and non-Bayesian inference; conjunction assessment and collision avoidance; data association; multitarget tracking; vision-based navigation; terrain relative navigation; extended object tracking; and attitude dynamics, determination, and control.